Karen Waller’s PhD looked at investigating blood-borne viruses in solid organ transplantation. She is the recipient of an NHMRC postgraduate research scholarship (2019). Watch the video below to hear more about her work.
an Australian Cohort Study 2010-2018 With hepatitis C (HCV) curative therapy, more potential donors may now be suitable. We sought to describe potential deceased donors with increased BBV transmission risk. We conducted a cohort study of all potential organ donors referred in New South Wales,… Read More »Characteristics and Donation Outcomes of Potential Organ Donors Perceived to be at Increased Risk for Blood Borne Virus Transmission
We aimed to quantify post-transplant viral infections, specifically those transmitted by donors and those reactivating or arising new in recipients. Find full text here: New blood-borne virus infections among organ transplant recipients: An Australian data-linked cohort study examining donor transmissions and other HIV, hepatitis C… Read More »New blood-borne virus infections among organ transplant recipients: An Australian data-linked cohort study examining donor transmissions and other HIV, hepatitis C and hepatitis B notifications (project: SAFEBOD)
The Safety and Biovigilance in Organ Donation (SAFEBOD) study aims to improve estimates of infection and cancer transmission risk and explore how real-time data access could support decision-making. Find the full text here: Safety and Biovigilance in Organ Donation (SAFEBOD): Protocol for a Population-Based Cohort… Read More »Safety and Biovigilance in Organ Donation (SAFEBOD): Protocol for a Population-Based Cohort Study
The CELESTIAL study is a cohort study using data linkage to compare people with end stage kidney disease (ESKD) and living kidney donors versus the general population. The datasets of people with ESKD, living kidney donors in Australia and New Zealand, and the Australians and… Read More »CELESTIAL – Cause of death for living kidney donors and people with end stage kidney disease, in Australia and New Zealand; a data linkage study
The ASSET project aims to use data linkage of existing health and administrative data in New Zealand, to create a platform for investigating issues of equity in delivery of health services for kidney transplantation. We are interested in investigating the impact of social determinants of… Read More »ASSET NZ – AcceSS and Equity in Transplantation, New Zealand
On 4th August 2020, Sydney Health Partners’ Renal Stream presented NSW Has (Scientific) Talent – a competition which aimed to virtually showcase and support the ongoing nephrology clinical and basic science research occurring across New South Wales by Early Career Researchers. Of the many abstracts… Read More »Sydney Health Partners’ Renal Stream – NSW Has (Scientific) Talent 2020
During 1988-2013, of 5286 deaths in 17,628 kidney transplant recipients, 934(17.8%) were cardiac. Kidney transplant recipients had greatly increased risk of cardiac mortality compared to the general population, but this has improved over time. Although male recipients have higher absolute risk, female recipients have a… Read More »Cardiovascular Mortality in Transplant Patients; A Population-Based Cohort Study 1988-2013 in Australia and New Zealand (project: CELESTIAL)
We looked at the cause of death for all kidney transplant recipients in Australia and New Zealand 1980-2013. There were 5,284 deaths in 17,628 kidney transplant recipients including 1,061 (20%) cancer deaths. Our study showed cancer mortality in kidney transplant recipients was overall 3 times… Read More »Cancer mortality in kidney transplant recipients: An Australian and New Zealand population‐based cohort study, 1980–2013 (project: CELESTIAL)
Other research suggests patients treated over weekends experience poorer outcomes. One study performed in the USA suggested that fewer organ retrievals happen at weekends, and of those organs retrieved, more are discarded and not used than during the week. The CODE team thought it was… Read More »Weekend effect: analysing temporal trends in solid organ donation (project: ORCHARD)